Optimal regimens of sulfamethoxazole-trimethoprim for prophylaxis of pneumocystis pneumonia in patients with systemic rheumatic diseases: multi-center randomized open label trial
Not Applicable
- Conditions
- Pneumocystis pneumonia
- Registration Number
- JPRN-UMIN000031513
- Lead Sponsor
- Juntendo University School of Medicin
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 89
Inclusion Criteria
Not provided
Exclusion Criteria
1.Have contraindications to SMX/TMP 2.Have a history of PCP 3.Have received biologic agents 4.Have uncontrollable complications 5.Body weight below 40 kg 6.Being pregnant or a nursing woman 7.Being unable to start SMX/TMP within 14 days of starting prednisolone 8.Unable to give informed consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary endpoint was non-incidence rate of PCP at week 52.
- Secondary Outcome Measures
Name Time Method The secondary endpoint was drug continuation rate at week 52.