Glioblastoma broadband power as a longitudinal biomarker for tumor progressio
Recruiting
- Conditions
- 10029211glioblastomabrain tumor
- Registration Number
- NL-OMON54202
- Lead Sponsor
- Vrije Universiteit Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
(1) age > 17 years, (2) histopathologically confirmed glioma, (3) eligible to
start radiotherapy
Exclusion Criteria
(1) psychiatric disease or symptoms at the time of inclusion, (2) other
comorbidities of the central nervous system, particularly cerebrovascular
accidents, multiple sclerosis, Alzheimer*s disease, (3) insufficient mastery of
the Dutch language, (4) inability to communicate adequately. For the additional
MRI sequences, an exclusion criterium is incompatibility with MRI.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>(1) MEG/EEG brain activity at different timepoints during the disease, and (2)<br /><br>radiological and clinical markers of tumor growth</p><br>
- Secondary Outcome Measures
Name Time Method <p>(1) chemical exchange saturation transfer (CEST) MRI and resting-state<br /><br>functional MRI (rsfMRI) at a number of timepoints</p><br>