Arterial stiffness in systemic inflammatory disease
Not Applicable
Completed
- Conditions
- Renal and Urogenital - Other renal and urogenital disordersInflammatory and Immune System - Autoimmune diseasessystemic inflammatory disease ( e.g. systemic lupus erythematodes, periaortits )
- Registration Number
- ACTRN12610000843055
- Lead Sponsor
- PD Dr. Eisenberger
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
patients with active or chronic systemic inflammatory disease
- or patients arterial hypertension for more than 5 years
- healthy persons
- written informed consent
Exclusion Criteria
- cardiac arrhythmia
- patients / persons < 18 years of age
- women with a known pregancy
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method arterial stiffness measured by pulse wave velocity[at time of recruitment]
- Secondary Outcome Measures
Name Time Method -evaluation of cardiovascular risk factors<br>(e.g. laboratory serum parameters like cholesterol, glycated hemiglobin<br>tools: patient data information concering previous cardiovascular disease, smoking habits[at time of recruitment];endothelial dysfunction<br>test e.g. serum markers ( Assymmetric dimethylarginine)[at time of recruitment];arterial hypertension measured by automatic sphygnomanometry[at time of recruitment];evaluation of cardiovascular risk factors <br>(clinical assessment, medical tests)[at time of recruitment]
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link arterial stiffness to systemic inflammatory diseases like lupus and periaortitis?
Are there specific biomarkers that correlate with arterial stiffness in autoimmune disease patients?
How does arterial stiffness in systemic inflammatory disease compare to other cardiovascular risk factors in renal patients?
What are the potential adverse events associated with arterial stiffness monitoring in chronic inflammatory conditions?
What drug targets have shown promise in mitigating arterial stiffness in autoimmune and systemic inflammatory disorders?