CTRI/2014/08/004842
Completed
Phase 4
Evaluation of systemic and vascular inflammation by [18F]-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (FDG-PET/CT) in patients with moderate to severe psoriasis randomized to different drug regimens
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Health Condition 1: null- Patients with moderate to severe psoriasis
- Sponsor
- PGIMER
- Enrollment
- 16
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients on topical or active light therapy
Exclusion Criteria
- •Patients with chronic inflammatory disease like diabetes mellitus, uncontrolled hypertension with SBP 180 mmHg and DBP 95 mmHg, cardiovascular disease and with coagulopathy
- •2\.Patients on any systemic therapy for psoriasis like methotrexate, retinoids or biologics in preceding 6 weeks
- •3\.Patients on tobacco, alcohol use that is 2 drinks per day or intravenous drug use.
- •4\.Participated in a research study in preceding 6 weeks
- •5\.Major surgery within 3 months of imaging
- •6\.Pregnant females
- •7\.Lactating mothers
- •8\.Patient with liver disease
- •9\.Blood glucose level 150 mg/dl
- •10\.Any other inflammatory condition in the body that in the opinion of investigator may jeopardise the validity of the study or put the patients at the greater risk
Outcomes
Primary Outcomes
Not specified
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