Evaluation of the inflammation and effects of dental denture during orthodontic treatme

Not Applicable

Recruiting

• Conditions: Orthodontic brackets; gingival crevicular fluid; Dental enamel; E06.658.453.590; A12.383.500; A14.549.167.900.255

• Registration Number: RBR-3sqsh8
• Lead Sponsor: Centro Universitário do Maranhão

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-07-09
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Patients aged between 18 and 40 years will be included; who agree and sign the informed consent form (TCLE); with good oral health in general, with the presence of all upper teeth up to the first molar with vitality, free of caries lesions; and may have satisfactory aesthetic restorations, proven by periapical radiographs that do not involve the middle third of the dental crown; without cervical lesions (abrasion, erosion and abduction); absence of periodontal disease; have not undergone periodontal treatment within 3 months prior to the start of the study; do not present clinical signs of gingivitis and do not have systemic disorders that interfere with the periodontal condition, prior to the installation of the device; non smokers; have not undergone previous orthodontic treatment; have not used antibiotics in the 3 months prior to the study; not being on systemic medication; the initial color of the teeth should be A2 or darker by comparison with the Vita Classic scale (Vita Zahnfabrik, Bad Säckingen, Germany) organized in order of value

Exclusion Criteria

The study will exclude patients who had undergone tooth whitening treatment in the last 12 months; with caries, cervical lesions; pregnant or lactating women; root canal treatment; patients with restorations at buccal surface or dental prosthesis on the teeth; gingival recessions; parafunctional habits; patients who were taking medications with an analgesic or anti-inflammatory effect

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The increase in the inflammatory activity, determined by quantification of the volume of gingival fluid measured in the phases: pre and post bleaching;The increase in the inflammatory activity, determined by evaluation of the proinflammatory cytokine levels, measured in the phases: pre and post bleaching

Secondary Outcome Measures

Name	Time	Method
Enamel color changes under orthodontic brackets bonded to superior premolars submitted to dental bleaching during orthodontic treatment