Echocardiographic Evaluation of the Change on Pulmonary Blood Flow and Cardiac Function During One-lung Ventilation
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Video-assisted Thoracic Surgery
- Sponsor
- Yonsei University
- Enrollment
- 25
- Locations
- 1
- Primary Endpoint
- The change of pulmonary blood flow
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
The investigators used transesophageal echocardiography (TEE) to assess the change of pulmonary blood flow and bi-ventricular function during lung isolation. The investigators hypothesized that changes in pulmonary venous flow with lung isolation may be related the shunt fraction and oxygenation during one lung ventilation (OLV). The investigators also observed the cardiac function during two lung ventilation (TLV) and OLV in supine and lateral position by TEE.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Above 20 years of age.
- •American Society of Anesthesiologists (ASA) Physical Status I and II
- •Thoracic surgical procedure (video-assisted)
Exclusion Criteria
- •severe functional liver or kidney disease
- •cardiac disease
- •arrhythmia
- •exceed BMI \> 30 kg/ m2
- •pathologic esophageal lesion (esophageal stricture or varix )
- •pregnancy
Outcomes
Primary Outcomes
The change of pulmonary blood flow
Time Frame: two-lung ventilation in the supine (T1) and lateral position (T2) and 10 (T3), 20 (T4), and 30 min (T5) during OLV in the left lateral decubitus position.
Pulmonary blood flow = PVA(cross sectional area of LUPV) x VTI(velocity time integral) x HR , Fractional area change = \[(LVAd-LVAs)/LVAd\] × 100 Ejection fraction = \[(LVEDV(LV end-diastolic volume) -LVESV(LV end-systolic volume)/LVEDV\] × 100
Secondary Outcomes
- The changes of respiratory parameters(two-lung ventilation in the supine (T1) and lateral position (T2) and 10 (T3), 20 (T4), and 30 min (T5) during OLV in the left lateral decubitus position.)
- The change of cardiac function(two-lung ventilation in the supine (T1) and lateral position (T2) and 10 (T3), 20 (T4), and 30 min (T5) during OLV in the left lateral decubitus position.)