A study of supplementation with Curcumin to Diabetics

Completed

• Conditions: Diabetes mellitus; Nutritional, Metabolic, Endocrine; Non-insulin-dependent diabetes mellitus

• Registration Number: ISRCTN49723587
• Lead Sponsor: Public Health College - Harbin Medical University (China)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-06-14
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1. Type 2 diabetes mellitus; the condition of patients are stable
2. Fasting blood glucose greater than or equal to 7.8 mmol/L or postprandial blood glucose greater than or equal to 11.1 mmol/L
3. Aged 18 - 65 years, both male and female

Exclusion Criteria

1. Type I diabetes
2. Pregnant or lactating women, or allergic to the tested samples
3. Have history of liver, kidney, hypertension, mental illness, taking other hypoglycaemics
4. People are uncooperative
5. Have diabetic ketosis, acidosis and infection in recent 3 months
6. Taking correlated medications which could potentially influence the purpose of this study
7. Failing to take drugs or the information is incomplete

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Amended as of 21/09/2010:<br>1. Lipids (triglycerides [TG], total cholestrol [TC], low-density liporotein cholesterol [LDL-C], high-density lipoprotein cholesterol [HDL-C])<br>2. Free fatty acids (FFAs)<br>3. Lipoprotein lipase (LPL)<br>4. Adipocyte fatty acid-binding protein (AFABP)<br>5. Liver ultrasonography<br>6. HbA1c<br>7. Apolipoproteins (ApoA1/ApoB)<br>8. Triacylglycerol<br>9. Cholesterol<br>10. 2-hour post-prandial glucose<br>11. Homeostasis model assessment - insulin resistance (HOMA-IR)<br><br>Initial information at time of registration:<br>1. Glucose<br>2. Insulin

Secondary Outcome Measures

Name	Time	Method
Amended as of 21/09/2010:<br>1. Age<br>2. Body mass index (BMI)<br>3. Diabetes duration<br>4. Cigarette use<br>5. Physical activity level<br>6. Food Frequency Questionnaire (FFQ)<br><br>Initial information at time of registration:<br>1. Red blood cell<br>2. White blood cell<br>3. Haemoglobin<br>4. Total protein<br>5. Albumin<br>6. Urea nitrogen<br>7. Creatinine<br>8. Alanine transaminase<br>9. Aspartate transaminase<br>10. Platelet count<br>11. Height<br>12. Weight<br>13. Waist circumference<br>14. Hip circumference<br>15. Blood pressure