Is a Neurocognitively Enriched Exercise Effective in Reducing Re-Injury Risk and Improving Balance and Proprioception in Individuals With Lateral Ankle Instability?
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 36
- 试验地点
- 2
- 主要终点
- Cumberland Ankle Instability Tool (CAIT)
研究概览
简要总结
In the general population, 19.0-26.6 per 1000 cases of ankle instability have been reported, while in the athletic population, the rate is 11.3 per 1000. Ankle instability also predisposes individuals to recurrent instability, leading to persistent symptoms. After ankle injuries, temporary increases in afferent activity, along with long-term deficits in somatosensory information from ligaments, may cause central neuroplasticity that affects sensorimotor function. This central neuroplasticity can lead to permanent dysfunctions in the affected limb, thereby increasing the likelihood of developing and maintaining chronic ankle instability (CAI). In addition to the association between impaired balance and reduced proprioception with CAI, it has been reported that the central nervous system may fail to manage joint stress due to its inability to discern load on the ligaments.
Impaired neurocognition has been linked to decreased performance and higher rates of re-injury. Deficiencies in neuromuscular control, motor learning, or other neurocognitive components related to an individual's performance and safety may affect the ability to respond appropriately in a dynamic environment. Any deficiencies in these neurocognitive processes can hinder the successful completion of tasks.
The aim of this study is to comparatively examine the effects of neurocognitively enriched rehabilitation versus traditional rehabilitation on re-injury risk, balance, and proprioception in individuals with a history of ankle instability.
详细描述
Voluntary participants who have been diagnosed with lateral ankle instability will be included in the study. Signed voluntary consent will be obtained from participants. Participants will be divided into two groups. Study groups will be as follows: a) Neurocognitive Enriched Exercise, b) Multimodal Exercise.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
盲法说明
The assessor will not know which participant received which intervention.
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The documented unilateral ankle instability confirmed through clinical examinations (drawer test, talar tilt test) and MRI in cases requiring differential diagnosis.
- •A history of an initial ankle sprain occurring at least 6 months ago.
- •The presence of a recurrent sense of giving way that started at least 6 months ago and has been intermittently persistent.
排除标准
- •Presence of a history of previous surgery in the lower extremity.
- •Identification of organic and non-organic lesions such as cartilage injuries, periarticular tendon tears, and impingement syndromes.
- •The existence of a fracture accompanying instability in the foot-ankle.
- •Presence of congenital deformities in the foot-ankle.
- •Diagnosis of talus osteochondral lesion.
- •Diagnosis of ankle arthritis.
- •Presence of medial ligament lesion.
- •Existence of peripheral neuropathy.
- •Presence of additional rheumatological diseases.
- •Regular moderate-level exercise for at least 3 days a week in the last 6 months.
结局指标
主要结局
Cumberland Ankle Instability Tool (CAIT)
时间窗: change from baseline at 6 months
It is a 30-point, 9-item scale measuring the severity of functional ankle instability. Lower scores indicate functional ankle instability. The Minimal Clinically Important Difference for this valid and reliable scale is 3 points.
Surface Electromyography-maximum voluntary isometric contraction
时间窗: change from baseline at 6 months
Electrode placements will be performed in accordance with the European Recommendations from Surface EMG for Non-Invasive Assessment of Muscles (SENIAM).
Surface Electromyography-muscles' normal functional activities
时间窗: change from baseline at 6 months
Electrode placements will be performed in accordance with the European Recommendations from Surface EMG for Non-Invasive Assessment of Muscles (SENIAM).
次要结局
- Ultrasonography(3 times for 24 weeks)
- Numeric Pain Rating Scale(3 times for 24 weeks)
- Joint Range of Motion Evaluation(3 times for 24 weeks)
- Tampa Kinesiophoby Scoring(3 times for 24 weeks)
- Star Excursion Test(3 times for 24 weeks)
- Single Leg Stance Test(3 times for 24 weeks)
- The Side Hop Test(3 times for 24 weeks)
- Global Rating of Change Scale-GRC(2 times for 52 weeks)
- Reproduction Test(3 times for 24 weeks)
研究者
Aysenur Erekdag
Principal Investigator
Istanbul University - Cerrahpasa