*Project *PLING*: development of a home-based app which uses Perceptual Learning to improve vison in children with Infantile NystaGmus*

Completed

• Conditions: infantile nystagmus syndrome; 10010463

• Registration Number: NL-OMON47749
• Lead Sponsor: Radboud Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 70

Inclusion Criteria

Children with infantile nystagmus:
- Age 7-18 years
- Diagnosis albinism (with infantile nystagmus) or idiopathic infantile nystagmus
- Binocular visual acuity >=20/400 and < 20/20.
- No additional (neurological or motor) impairments
- Born at term with normal birth weight (>=3000 gr);Children with normal vision:
- Age 8-18 years (n = 30)
- Binocular visual acuity >=20/20
- Born at term (>30 weeks) with normal birth weight (>3000 gr)

Exclusion Criteria

Children with infantile nystagmus:
- Received computerized visual perceptual learning before
- Neurological conditions such as cerebral visual impairment, oculomotor apraxia, hemianopia, developmental disorders.
- Visual acuity <20/400 or >= 20/20. ;Children with normal vision:
- Motor or mental impairments;
- The presence of a developmental disorder;
- Binocular visual acuity <20/20.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Intervention study + validation study:<br /><br>- Near and distance visual acuity<br /><br>- Crowding intensity</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Intervention study:<br /><br>- Contrast sensitivity function<br /><br>- Stereopsis<br /><br>- Reading performance<br /><br>- Eye movements (fixation stability and saccade execution)<br /><br>- Compliance<br /><br>- Training joy<br /><br>- Vision related quality of life </p><br>