Metabolic effects at two months from a fasting week
Not Applicable
Completed
- Conditions
- Clients of the Centre Interlude Bien-être, where a week of fasting is done voluntarilyNot Applicable
- Registration Number
- ISRCTN90206986
- Lead Sponsor
- Fondazione Hospice Ticino
- Brief Summary
2021 Results article in https://doi.org/10.3390/nu13010255 (added 11/05/2021)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
1. Informed consent
2. Participating in a fasting week at the Centre Interlude Bien-être
3. Age = 20 years, = 70 years
Exclusion Criteria
1. Diabetes mellitus or taking glucose-lowering medication
2. BMI <18kg/m2
3. Known eating disorders (orthorexia, anorexia, bulimia)
4. Known metabolic pathologies that contraindicate fasting (e.g. deficiencies gluconeogenesis)
5. Pregnant women or during the lactation period
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Plasma LDL cholesterol (laboratory analysis in mmol/l) measured at the onset of fasting and two months after the beginning of the fasting week, in the group selected for blood sampling
- Secondary Outcome Measures
Name Time Method <br> 1. Total cholesterol (mmol/l), HDL cholesterol (mmol/l), triglycerides (mmol/l), blood glucose (mmol/l), CRP (mg/l) and IGF-1 (ng/ml), in the group selected for blood sampling (laboratory analysis), and variation in BMI (kg/m2), CA (cm), TA (mmHg), heart rate (/min), temperature (°C), measured at the beginning of the fast and 2 months after<br> 2. The same measures (and LDL cholesterol) at the beginning and at the end of the fast<br> 3. Fat-free mass measured by bioelectrical impedance analysis at 50 kHz with Nutrigard MS performed at the beginning, end and 2 months after the beginning of the fast<br>