NCT05820321Unknown不适用
Effects of Dietary Nitrate Intake on Physical Performance of Middle-aged Women: a Randomized Trial
适应症
干预措施
试验速览
- 阶段
- 不适用
- 入组人数
- 15
- 试验地点
- 2
- 主要终点
- Handgrip strength test (kgf)
研究概览
简要总结
Through a randomized, crossover, triple-blind, placebo-controlled clinical trial, 15 physically inactive hypertensive women will participate a 8-day trial, each with two intervention protocols: 1) placebo and 2) beetroot; in which will ingest beet juice with or without NO3 in its composition with a 8-day washout interval.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 50 Years 至 65 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •50 to 65 years old
- •Physically inactive
- •Postmenopausal diagnosis (amenorrhea for 12 months or more);
排除标准
- •Cardiac failure
- •Previous history of acute myocardial infarction and/or stroke;
- •Allergy or intolerance to nitrate, gluten, or milk;
研究组 & 干预措施
Experimental (Beetroot juice NO3)
Active Comparator
8-day supplementation with beetroot juice rich in NO3 (400mg) during 8 days.
干预措施: Beetroot juice rich in nitrate (Dietary Supplement)
Placebo (Beetroot juice without NO3)
Placebo Comparator
8-day supplementation with beetroot juice NO3 depleted during 8 days.
干预措施: Beetroot juice NO3 depleted (Other)
结局指标
主要结局
Handgrip strength test (kgf)
时间窗: up to 2 years
次要结局
- Sit-to-stand test (repetitions)(up to 2 years)
- Arm curl test (repetitions)(up to 2 years)
- 8-foot up and go test (seconds)(up to 2 years)
- Six minute walk test (distance in meters)(up to 2 years)
研究者
Cicero Jonas R Benjamim
Principal investigator
University of Sao Paulo
研究点 (2)
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