The role of isoniazid medication in preventing progression to active tuberculosis disease in persons with latent tuberculosis: The effect on the body’s immune system
Not Applicable
Completed
- Conditions
- atent tuberculosis infectionInfections and InfestationsTuberculosis
- Registration Number
- ISRCTN15705625
- Lead Sponsor
- College of Health Sciences, Makerere University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 145
Inclusion Criteria
Household contacts exposed to patients with sputum smear positive tuberculosis that are:
1. Above the age of 5 years
2. HIV negative
3. Tested positive on both the tuberculin skin test and the QuantiFERON®-TB Gold In-Tube® test (Cellestis GmbH (Europe), Hannover, Germany; QFN)
Exclusion Criteria
Household contacts excluded if they have:
1. Signs and symptoms of active tuberculosis
2. Liver disease
3. Epilepsy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method