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Isoniazid or Rifampicin and Isoniazid Preventive Therapy for children exposed to TB - the IRIPT trial

Not Applicable
Conditions
Tuberculosis
Paediatrics
Registration Number
PACTR201101000273931
Lead Sponsor
Christian Wejse
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Other
Sex
All
Target Recruitment
880
Inclusion Criteria

1)Household contact of TB case
2)Age<5 years or
age 5-14 years + a positive TST (>5mm)
3)Informed consent given by parent or person in loco parentis

Exclusion Criteria

1)Active TB at time of inclusion
2)HIV-positive child receiving HAART
3)Known liver disease or allergy to INH or RIF
4)Pregnancy (all girls>12 years will get a pregnancy test)
5)A history of seizures

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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