USE OF DADIMADYA GHRUT IN KIDNEY FAILURE

Phase 2/3

Not yet recruiting

• Conditions: Type 2 diabetes mellitus with kidney complications. Ayurveda Condition: E1121,

• Registration Number: CTRI/2025/05/087058
• Lead Sponsor: Dr.Onkar Ankushrao Kande

Brief Summary

Summary of Research Study

Study Title

An open Randomized controlled clinical trial of Gokshuradi guggulu and Dadimadya ghrut Matra basti in Diabetic Nephropathy.



Objective

To assess the efficacy of Gokshuradi guggulu and Dadimadya ghrut Matra basti in managing Diabetic Nephropathy compared to standard care.



Methodology

The study will include patients with Diabetic Nephropathy (Grade 2 Kidney Disease) and albumin creatinine ratio (ACR) >30 mg/dl. Patients will be randomly assigned to receive either Gokshuradi guggulu and Dadimadya ghrut Matra basti or standard care.



Outcome Measures

The study will evaluate the efficacy of the treatment using objective criteria such as:



1. Albumin creatinine ratio (ACR)

2. eGFR value

3. Urine routine and microscopic

4. HBA1C value



Expected Outcome

The study aims to determine if Gokshuradi guggulu and Dadimadya ghrut Matra basti is more effective in managing Diabetic Nephropathy than standard care.

Detailed Description

Not available

Study Timeline

• Study Start: 2025-05-20
• Last Update Posted: 2025-07-05

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

AC Ratio ( 30- 300 mg/g).

Exclusion Criteria

• Age below 18 yrs and above 80 yrs.
• Acute life threatening condition.
• Immuno compromised patients.
• Type I Diabetes Pregnancy and lactating female.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
basti is effective in management of Diabetic Nephropathy .	3 MONTHS
basti	3 MONTHS
Matra	3 MONTHS
Assessment of the efficacy of Gokshuradi guggulu and	3 MONTHS
Dadimadya ghrita	3 MONTHS

Secondary Outcome Measures

Name	Time	Method
To find out the effect of Gokshuradi guggulu &	Dadimadya

Trial Locations

Locations (1)

YMT AYURVEDIC MEDICAL COLLEGE AND HOSPITAL; 🇮🇳 Raigarh, MAHARASHTRA, India

YMT AYURVEDIC MEDICAL COLLEGE AND HOSPITAL

🇮🇳Raigarh, MAHARASHTRA, India

DrOnkar Ankushrao Kande

Principal investigator

8888989594

kandedronkar@gmail.com