To determine the effectivity of working of oral midodrine tablet in preventing fall in Blood pressure after spinal anesthesia in all lower limb and below abdomen surgeries by giving the tablet before spinal anesthesia
Phase 3
Not yet recruiting
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/07/055663
- Lead Sponsor
- Rakshitha R
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA grade 1
Patients undergoing lower abdomen and lower limb surgeries
Patients without local anesthesia toxicity
Exclusion Criteria
1. Patients with history of hypertension, cardiovascular disease, cerebrovascular disease, baseline SBP >140mm Hg before administration of drug
2. Patients with any contraindications to spinal anesthesia
3. History of coagulopathy, pheochromocytoma.
4. Patients on vasoconstrictors.
5. Pregnancy .
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms does midodrine target to prevent hypotension after spinal anesthesia?
How does preoperative oral midodrine compare to intravenous phenylephrine in managing spinal anesthesia-induced hypotension?
Are there specific biomarkers that predict patient response to midodrine in infraumbilical surgeries?
What adverse events are associated with preoperative midodrine use and how are they managed?
What are the potential combination therapies with midodrine for enhanced hypotension prevention in spinal anesthesia?