Visualizing tinnitus with fMRI.
- Conditions
- ringing in the ears1002766710029305
- Registration Number
- NL-OMON34095
- Lead Sponsor
- niversiteit Twente
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 72
General:
- Men and women;
Tinnitus patients:
- Unilateral tinnitus;
- Perception of a tone;
- Tinnitus perception for more than 1 year;
- Unchanged tinnitus perception (pitch, amplitude, side) for more than 6 months.
Hearing impaired non-tinnitus:
- Perceptive hearing impairment
General:
- Age < 18 years;
- MRI contraindications;
- Claustrophobia;
- Ear inflammation;
- Other ear diseases like acoustic neuroma;
- Diagnosed neurological or psychiatric disease;
- Conductive hearing impairment.
Tinnitus patients:
- Perception of noise;
- Pulsatile tinnitus.
Normal hearing subjects:
- Conductive hearing impairment;
- Use of hearing aids;
- (history of) Menières disease;
- (history of) tinnitus perception.
Hearing impaired non-tinnitus:
- Conductive hearing impairment;
- (history of) Menières disease;
- (history of) tinnitus perception.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main fMRI study parameter is the number of active voxels in the auditory<br /><br>cortex and the inferior colliculus. The amount of active voxels is a measure<br /><br>for the amount of activation caused by the application of the stimuli. The<br /><br>number of voxels is determined by comparing both tinnitus matching and<br /><br>non-matching stimuli to the silence. </p><br>
- Secondary Outcome Measures
Name Time Method <p>A secondary fMRI study parameter is the number of active voxels in other areas<br /><br>of the brain. The AC and IC are the most important, but not the only neural<br /><br>correlates of tinnitus. Activity found in other regions of the brain is also<br /><br>taken into account for further analysis.</p><br>