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eural reorganization in tinnitus: a high-field fMRI study

Conditions
tinnitus, phantom sound perception (NL: oorsuizen)
Registration Number
NL-OMON23745
Lead Sponsor
Maastricht University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
26
Inclusion Criteria

The main inclusion criteria of the patient groups are:

•Male or female between 18 and 75 years

Exclusion Criteria

Exclusion criteria of the patient groups are:

•Fletcher Index > 50 dB HL for both ears (i.e., mean of hearing loss in decibels for 1k, 2k and 4k Hz)

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The link between frequency tuning and tinnitus will be tested by comparing the size and response magnitude of the auditory cortex regions that show tuning to the patient’s specific tinnitus frequency vs. regions that show tuning to the other (non-tinnitus) frequencies. In this way, patients can serve as their own controls, in addition to matching healthy controls.
Secondary Outcome Measures
NameTimeMethod
Furthermore, anatomical features (measures of myelin content and cortical thickness) will be assessed in the same regions of interest as mentioned in the primary outcome.
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