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Enhancing Treatment Adherence in Pediatric Asthma With a Problem Solving Intervention

Not Applicable
Completed
Conditions
Asthma
Interventions
Behavioral: Tailored Problem Solving Intervention
Behavioral: Family Education Intervention
Registration Number
NCT00149487
Lead Sponsor
Case Western Reserve University
Brief Summary

The purpose of this study is to determine the effectiveness of a tailored problem solving intervention in increasing adherence to asthma management behaviors in African American adolescents with asthma.

Detailed Description

BACKGROUND:

Children and adolescents who are unable to adhere to their medical regimen for the management of chronic illness present considerable challenges to health care providers and researchers. Pediatric asthma is a chronic illness where the consequences of non-adherence are particularly detrimental and widespread, especially among economically disadvantaged minority children and their families. Studies of intervention of asthma management are needed for this population.

DESIGN NARRATIVE:

The aim of the proposed study is to test the efficacy of a problem solving intervention that is tailored to the observed adherence behaviors and identified barriers to increasing adherence in African American children and adolescents with asthma, and their families. Patients are randomized to either a Tailored Problem Solving Intervention, or a control group who will receive Family Education Intervention. Duration of the intervention is four months.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
120
Inclusion Criteria
  • African American
  • Family income to be below the poverty line
  • Physician-based diagnosis of asthma of at least 12 months
  • Moderate to severe asthma (moderate asthma includes daily symptoms, daily use of inhaled short acting beta-agonist, exacerbations greater than 2 times per week that affect activity, and nighttime symptoms greater than once a week, FEV1 or Peak Flow PEF between 60 and 80 percent predicted and PEF variability greater than 30 percent; severe asthma includes continual symptoms, limited physical activity, frequent exacerbations together with frequent nighttime symptoms, FEV1 or PEF less than 60 percent predicted, and PEF variability greater than 30 percent)
  • Likely to be on a stable and daily medication (inhaled steroid) that can be modified electronically for the time period required to participate in the study
Exclusion Criteria
  • Presence of a serious comorbid chronic condition

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Experimental: Tailored Problem Solving InterventionFamily Education InterventionParticipants will be randomized to follow a tailored problem solving intervention for the child.
Control: Family Education InterventionFamily Education InterventionParticipants will be randomized to follow a family education intervention.
Experimental: Tailored Problem Solving InterventionTailored Problem Solving InterventionParticipants will be randomized to follow a tailored problem solving intervention for the child.
Control: Family Education InterventionTailored Problem Solving InterventionParticipants will be randomized to follow a family education intervention.
Primary Outcome Measures
NameTimeMethod
Adherence to medical treatment, based on electronic monitors3, 6, 9 and 12 months

describe the trajectories of adherence to daily inhaled corticosteroid (ICS) medication for a year in economically disadvantaged, African-American youth with asthma based on growth curve modeling

Secondary Outcome Measures
NameTimeMethod
Asthma-related morbidity, including symptoms, pulmonary functioning, and health-related quality of life3, 6, 9 and 12 months

test the relationship of treatment adherence to symptom control, quick-relief medication, and healthcare utilization.

Trial Locations

Locations (1)

Case Western Reserve University

🇺🇸

Cleveland, Ohio, United States

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