Skip to main content
Clinical Trials/NCT05078606
NCT05078606
Completed
N/A

Pre-anesthetic Ultrasonographic Assessment of Neck Vessels as Predictors of Spinal Anesthesia Induced Hypotension in Elderly: a Prospective Observational Study.

Cairo University1 site in 1 country71 target enrollmentOctober 7, 2021

Overview

Phase
N/A
Intervention
Not specified
Conditions
Post-spinal Hypotension
Sponsor
Cairo University
Enrollment
71
Locations
1
Primary Endpoint
Accuracy of IJV collapsibility index as predictor of Spinal anesthesia induced hypotension.
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

Spinal anesthesia induces sympathetic blockade and venodilation, thus reducing venous return and the cardiac output. Therefore, assessment of intravascular volume deficit before anesthesia might predict a critical decrease in blood pressure after anesthesia.

Recently, ultrasonographic evaluation of the internal jugular vein (IJV) has been used to reflect intravascular volume status and fluid and as a predictor of hypotension after induction of general anesthesia.

Carotid intima-media thickness (CIMT) has been used to predict atherosclerosis-related events, such as stroke, myocardial infarction, peripheral artery disease, and hypotension after induction of anesthesia with a cut-off value of 0.65 mm of CIMT as a threshold level.

Detailed Description

This study aims to evaluate the ability of preoperative Ultrasonographic assessment of the internal jugular vein (IJV) and Carotid intima-media thickness (CIMT) to predict spinal anesthesia induced hypotension (SAIH). Participants will be elderly patients (above 60 years), ASA I-II-III, scheduled for elective surgeries under spinal anesthesia.

Registry
clinicaltrials.gov
Start Date
October 7, 2021
End Date
January 21, 2022
Last Updated
4 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Bassant M. Abdelhamid

Associate professor

Cairo University

Eligibility Criteria

Inclusion Criteria

  • Adult patients (\>60 years)
  • ASA I-II-III
  • Patients scheduled for elective surgeries under spinal anesthesia.

Exclusion Criteria

  • Operations which will last for less than 15 minutes.
  • Deep vein thrombosis in the upper extremities.
  • History of radiotherapy or neck surgery.
  • Previous sonographic data show tricuspid or mitral regurgitation or a very distended right atrium and ventricle.
  • Patients with history of valvular or carotid artery surgery, arrhythmia, heart failure.
  • Being unable to lie in a supine position for the necessary measurements.
  • Technical limitations to imaging of the IJV and carotid artery.

Outcomes

Primary Outcomes

Accuracy of IJV collapsibility index as predictor of Spinal anesthesia induced hypotension.

Time Frame: 10 minutes

(Area under receiver operating characteristic curves)

Secondary Outcomes

  • Accuracy of rate of change in IJV area with change in posture as a predictor of Spinal anesthesia induced hypotension.(10 minutes)
  • Carotid intima media thickness.(10 minutes)
  • Norepinephrine consumption(20 minutes)
  • Incidence of Spinal anesthesia induced hypotension(20 minutes)

Study Sites (1)

Loading locations...

Similar Trials