The Effects of Short-time High-intensity Interval Training on Tissue Glucose and Fat Metabolism in Healthy Subjects and Patients With Type 2 Diabetes

Turku University Hospital1 site in 1 countryApril 29, 2011

ConditionsType 2 Diabetes Mellitus Healthy Volunteers

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Type 2 Diabetes Mellitus
Sponsor: Turku University Hospital
Locations: 1
Last Updated: 15 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The objectives of this study are to investigate the effects of short-time high-intensity interval training on tissue glucose and fat metabolism in healthy lean subjects and type 2 diabetic patients using modern and noninvasive imaging methods positron emission tomography (PET), magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS).

Registry

clinicaltrials.gov

Start Date

April 29, 2011

End Date

TBD

Last Updated

15 years ago

Study Type

Interventional

Sex

Male

Investigators

Sponsor

Turku University Hospital

Eligibility Criteria

Inclusion Criteria

•The healthy patients
•BMI 18.5-30
•Fasting plasma glucose less than 6.1 mmol/l
•Normal glucose tolerance test (OGTT)
•The type 2 diabetic patients:
•Age-, sex-, and BMI-matched with the study subjects in the phase 1
•In a good treatment balance
•Glycated haemoglobin (HbA1c) less than 7.5 mmol/l
•Two hours glucose value in oral glucose tolerance test (OGTT) less than 10.0 mmol/l

Exclusion Criteria

•The healthy patients
•Blood pressure \> 140/90 mmHg
•Any chronic disease
•Any chronic medical defect or injury which hinder/interfere everyday life
•History of anorexia nervosa or bulimia
•History of rest or exercise-induced asthma
•Previous use of anabolic steroids, additives or any other substrates
•Smoking of tobacco, taking of snuffs, or use of narcotics.
•Significant use of alcohol
•Any other condition that in the opinion of the investigator could create a hazard to the subject safety, endanger the study procedures or interfere with the interpretation of study results