Evaluation of Diagnoses and Clinical Outcomes in Children Undergoing MRI Scans
- Conditions
- Magnetic Resonance Imaging
- Registration Number
- NCT06278376
- Lead Sponsor
- Jessa Hospital
- Brief Summary
The aim of this study is to evaluate the indications and therapeutical consequences of MRI scans of (young) children undergoing risky remote anaesthesia. The investigators want to aim for a clear indication in children undergoing MRI in the future before undergoing possible unnecessary procedures and MRI scans.
- Detailed Description
Magnetic resonance imaging (MRI) is a non-invasive imaging technique that allows physicians to visualize our anatomy, generating high-quality pictures of our body's internal structure at many different angles. The principle behind MRI, known as nuclear magnetic resonance (NMR), revolves around hydrogen atoms (or protons) that can be found everywhere in our entire body, such as in bones, blood, organs, skin, muscles and more. Protons have their own magnetic moment and angular momentum, allowing them to spin in a certain direction. By subjecting these spinning protons to a strong magnetic field they will be oriented along the axis of the magnetic field, either with or against the direction of the magnetic field. MRI machines generate this field using a large magnet surrounding the patient. Electric gradient coils allow the strength of the field to be adjustable, usually around 0,5 or 1,5 tesla.
MRI has many advantages compared to other imaging techniques, i.e. CT (computed tomography), including the lack of radiation, the ability to show abnormalities of soft tissues, the ability to visualize blood flow, and contrasting agents that are less likely to cause adverse effects like allergic reactions. There are also some disadvantages or limitations, however: implants or metallic objects inside the body can make images unclear at best or harm the patient at worst; similarly, movements made by the patient can make images unclear as well. Lastly, MRI is a more expensive and slower technique compared to other imaging techniques.
Children undergoing an MRI are often sedated before being placed inside the machine. After the scan is over, the children will be brought to a recovery area, where they can slowly recover from the sedation until they are fully awake again. Some common side effects resulting from the sedation may be vomiting, drowsiness and/or dizziness.
The aim of this study is to evaluate the indications and therapeutical consequences of MRI scans of (young) children undergoing risky remote anaesthesia. The investigators want to aim for a clear indication in children undergoing MRI in the future before undergoing possible unnecessary procedures and MRI scans.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 410
- Children undergoing an MRI scan in Jessa hospital (Hasselt, Belgium) between November 2016 and February 2023.
- Age between 6 months and 16 years
- /
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence Between 2016 and 2023 Incidence of diagnostic MRI in childeren
- Secondary Outcome Measures
Name Time Method Clinical indications Between 2016 and 2023 Evaluating the clinical indications for the MRI investigation
Clinical outcome: mortality Between 2016 and 2023 Evaluation of the clinical outcome: mortality after MRI
Evaluation of body part Between 2016 and 2023 Evaluating which specific body parts are undergoing imaging
Therapeutical implications: treatment Between 2016 and 2023 Evaluating if the MRI investigation resulted in treatment (drug treatment, surgery or physiotherapy)
Influence of COVID-19 pandemic Between 2016 and 2023 Influence of COVID-19 pandemic (2020-2021 versus 2016-2017-2018-2019-2022-2023) on incidence, therapeutical implications and outcomes of MRI scans in children
Clinical outcome: admission to hospital Between 2016 and 2023 Evaluation of the clinical outcome: admission to hospital
Therapeutical implications: diagnosis Between 2016 and 2023 Evaluating the presence of a diagnosis after this MRI investigation
Evaluation of age Between 2016 and 2023 Evaluation of age in children: \<2 years, 2-6 years and \>6 years
Evaluation of symptoms Between 2016 and 2023 Evaluation of the pre-existing symptoms (vomiting, headache, developmental delay, sleep issures, swellings, seizures, balance problems, conduct disorders, febrile convulsions) that potentially lead to an MRI scan
Clinical outcome: adverse event Between 2016 and 2023 Evaluation of the clinical outcome: adverse events
Clinical outcome: surgery Between 2016 and 2023 Evaluation of the clinical outcome: surgery after MRI
Trial Locations
- Locations (1)
Jessa hospital
🇧🇪Hasselt, Belgium