The Effect of Nitrate Supplementation on Sports Performance: Duration of Supplementation
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 3
- 主要终点
- Time-trial exercise performance
研究概览
简要总结
The main aim of the current study will be to find the optimal duration of supplementation to enhance sports performance.
详细描述
Oral ingestion of nitrate (NO3-) in the form of both nitrate salts and beetroot juice has been shown to significantly lower blood pressure at rest and to also lower pulmonary oxygen uptake during exercise, in addition to improving exercise performance during cycle time trial. However, there has been no consensus on the optimal supplementation protocols, in terms of duration of supplementation to see these metabolic effects. Furthermore, a positive exercise performance effect of nitrate ingestion has primarily been observed in recreational athletes. The potentially ergogenic effects of nitrate in well-trained or elite athletes therefore remain to be fully established. Based on the gaps in current literature, our main goal will be to gain further insight into different aspects of nitrate supplementation to enhance (elite) sports performance. This will be investigated in this study by assessing the effect of an acute vs. chronic supplementation period of sodium nitrate (NaNO3-) on exercise performance.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •18.5 < BMI < 25 kg/m2
- •Endurance trained cyclists/triathletes (with at least 1 year of competitive cycling experience)
- •VO2max ≥ 55 mL/kg/min
排除标准
- •Use of medication
- •Injury prohibiting them from performing the exercise protocol effectively
- •Currently supplementing diet with nitrate
- •Lactose intolerance
结局指标
主要结局
Time-trial exercise performance
时间窗: Time trial starts 4 hours after ingestion and ends on average after 15 minutes of cycling (depending on subject's cycling speed)
The primary outcome measure will be the time to complete the time-trial following dietary nitrate or placebo ingestion
次要结局
- Plasma nitrate and nitrite levels(30 min pre-ingestion until 30 min post-time-trial testing)
- Resting blood pressure(30 min pre-ingestion until 2.5 hours post-ingestion)
- Time-trial exercise performance; power output and heart rate(starting from 4 hours post-ingestion on testing days until completion of the time-trial)
- Submaximal exercise performance(starting from 3 hours post-ingestion on testing days until completion of the submaximal exercise)