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Dexmedetomidine blunts the transient cardiovascular changes induced by inhalation of desflurane.

Not Applicable
Recruiting
Conditions
Not Applicable
Registration Number
KCT0002157
Lead Sponsor
Kyung Hee University Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
60
Inclusion Criteria

1) Adult patients undergoing elective surgery with general anesthesia at Kyung Hee University Hospital in Seoul
2) Age of =19 and <65 years old patients
3) The American Society of Anesthesiologists (ASA) Physical Status(PS) I,II

Exclusion Criteria

1) Patients who disagree with participating in this study
2) Patients who have habitual abuse history in hypnotics, sedatives, etc.
3) Anemia or hematocrit < 24%
4) History of uncontrolled hypertension (systolic BP = 160 mmHg)
5) Preinduction systolic blood pressure = 90 mmHg
6) Preinduction heart rate =100 or = 45 beats/min
7) History of uncontrolled Diabetes mellitus(DM) (long lasting blood glucose over 200 mg/dL)
8) Pregnant women

Study & Design

Study Type
Interventional Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Systolic blood pressure;Diastolic blood pressure;Mean arterial pressure; Heart rate
Secondary Outcome Measures
NameTimeMethod
Complications (tachycardia(HR>130) or bradycardia(HR <40), arrhythmia;hypertension(SBP >190) or hypotension(MAP < 50)
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