Dexmedetomidine blunts the transient cardiovascular changes induced by inhalation of desflurane.
- Conditions
- Not Applicable
- Registration Number
- KCT0002157
- Lead Sponsor
- Kyung Hee University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
1) Adult patients undergoing elective surgery with general anesthesia at Kyung Hee University Hospital in Seoul
2) Age of =19 and <65 years old patients
3) The American Society of Anesthesiologists (ASA) Physical Status(PS) I,II
1) Patients who disagree with participating in this study
2) Patients who have habitual abuse history in hypnotics, sedatives, etc.
3) Anemia or hematocrit < 24%
4) History of uncontrolled hypertension (systolic BP = 160 mmHg)
5) Preinduction systolic blood pressure = 90 mmHg
6) Preinduction heart rate =100 or = 45 beats/min
7) History of uncontrolled Diabetes mellitus(DM) (long lasting blood glucose over 200 mg/dL)
8) Pregnant women
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Systolic blood pressure;Diastolic blood pressure;Mean arterial pressure; Heart rate
- Secondary Outcome Measures
Name Time Method Complications (tachycardia(HR>130) or bradycardia(HR <40), arrhythmia;hypertension(SBP >190) or hypotension(MAP < 50)