Effects of asthma medicine on physical performance in patients with COPD and changes in immune response after exercise
- Conditions
- To investigate the effects of terbutaline on repeated exercise performance in patients with chronic obstructive pulmonary disease (COPD). Furthermore to examine the inflammatory response during and after exercise in patients with COPD.Therapeutic area: Body processes [G] - Physiological processes [G07]
- Registration Number
- EUCTR2011-002987-26-DK
- Lead Sponsor
- Bispebjerg Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- Male
- Target Recruitment
- 10
Inclusion Criteria
-Sex: Male
-Age: 45-75
-COPD classified as GOLD2, with a FEV1 between 30 and 50%
-In a physical condition that allows cycling
-smoker or former smoker
-Informed consent
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 10
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
-Cardiovascular diseases
-Other respiratory diseases than COPD, as well as, lung cancer
-Allergy towards the study medicine
-Use of beta2-agonist 48 hours prior to study days
-COPD rehabilitation 3 months prior to study
-Patients treated with beta-blockers
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method