Information Needs Around Parenteral nUTrition in Cancer

Completed

• Conditions: Neoplasms; Malignancy; Tumor; Cancer; End Stage Cancer; Terminal Cancer; Malignant Neoplasm
• Interventions: Other: Non-interventional study

• Registration Number: NCT04495530
• Lead Sponsor: Royal Marsden NHS Foundation Trust

Brief Summary

This study will explore the information needs of patient's with advanced cancer, and their carers, when making a decision to commence or discontinue parenteral nutrition. Interviews will be conducted with both patients with advanced cancer, and their carers to determine the information they need to make a shared decision with the healthcare team.

Detailed Description

Parenteral nutrition (PN) is a type of nutritional liquid that is given directly into a vein, and is usually given when a person does not have a working gut. This type of nutrition is managed by a team of healthcare professionals and requires regular monitoring, such as bloods tests, to allow the team to provide the right balance of nutrients to the individual patient. This is an important decision, and the benefits, risks and consequences of having this type of nutrition should be fully explained to the patient and carer, to make sure they can make an informed decision. The aim of this study is to find out what information both patients and carers feel they need to be able to make a decision to start, and a later date stop, parenteral nutrition, with a diagnosis of advanced (incurable) cancer.

It is not clear if patients and carers get all the information they need before making this decision, and often the decision is made by a doctor and other healthcare professionals. However, patients and carers have a right to make decisions about their care. We will therefore interview patients and carers who have experience of making this decision, or in the process of making this decision, to find out what information is important to them. Our aim is to use the results from this research to improve the experience that patients and carers have in the future.

Study Timeline

• Study First Submitted: 2020-07-21
• Study First Submitted QC: 2020-07-28
• Study First Posted: 2020-08-03
• Study Start: 2021-01-19
• Primary Completion: 2022-06-30
• Study Completion: 2022-06-30
• Status Verified: 2022-07
• Last Update Submitted: 2022-07-14
• Last Update Posted: 2022-07-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

• Adults aged 18 years and over
• Fluent English speaker
• Is aware of diagnosis of advanced cancer
• Patient considering starting PN, is currently receiving PN or has previously received PN OR
• Carer of a patient considering, receiving or who has received PN
• NHS patient
• Assessed as having capacity to give consent and participate
• Current patient at one of the recruiting hospital sites

Exclusion Criteria

• Private patients

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Carer	Non-interventional study	Carers will be those caring for a patient with advanced cancer who is considering commencing or discontinuing parenteral nutrition, or already receiving parenteral nutrition. Carers will also be recruited if they previously cared for a person with advanced cancer receiving parenteral nutrition in the last 12 months
Patient	Non-interventional study	Patients will be considering commencing or discontinuing parenteral nutrition, or will be receiving home parenteral nutrition

Primary Outcome Measures

Name	Time	Method
The type of information that patients and carers need to make an informed decision to commence or discontinue parenteral nutrition	Through completion of study; expected 1 year	This exploratory study will provide insight into the information that patients with advanced cancer, and their carers need to make an informed decision to commence and discontinue parenteral nutrition

Secondary Outcome Measures

Name	Time	Method
How healthcare professionals should deliver information to patients and carers in order for them to make an informed decision to commence or discontinue parenteral nutrition	Through completion of study; expected 1 year	Patients and carers will provide insight into how they would like to receive information regarding parenteral nutrition from the clinical team. This may be through verbal or written communication.

Trial Locations

Locations (4)

St Mark's Hospital; 🇬🇧 London, United Kingdom

University College London Hospitals NHS Foundation Trust; 🇬🇧 London, United Kingdom

Royal Marsden Hospital NHS Foundation Trust; 🇬🇧 London, United Kingdom

St George's NHS Foundation Trust; 🇬🇧 London, United Kingdom