Investigating the levels of extrachromosomal circular DNA in serum of newly diagnosed type 2 diabetes mellitus patients

Not Applicable

• Conditions: Type 2 diabetes mellitus; Nutritional, Metabolic, Endocrine

• Registration Number: ISRCTN12415732
• Lead Sponsor: Wannan Medical College

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-12-21
• Last Update Posted: 5 January 2021
• Study Completion: 2021-07-01

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 42

Inclusion Criteria

1. Type 2 diabetes mellitus diagnosed according to the 1999 World Health Organization diagnostic criteria

Exclusion Criteria

1. No clinical evidence of severe kidney or liver diseases, chronic viral or bacterial infection, in?ammatory diseases, tumors, or diabetic ketoacidosis

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Serum eccDNA levels in peripheral blood samples of newly diagnosed type 2 diabetes mellitus patients measured using high throughput sequencing at the time of data collection

Secondary Outcome Measures

Name	Time	Method
1. Clinical factors associated with the differentially expressed eccDNA measured using patient records at the time of data collection