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临床试验/NCT02781337
NCT02781337招募中不适用

Epidemiological and Molecular Colorectal Cancer Registry

Hospital Italiano de Buenos Aires2 个研究点 分布在 1 个国家目标入组 2,100 人开始时间: 2012年5月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
2,100
试验地点
2
主要终点
Disease-free survival

研究概览

简要总结

This is a Registry that invites patients undergoing colorectal surgery for colorectal cancer. Epidemiological data is collected. The Registry includes tumor tissue and blood banks for analyzing different genetic mutations and disease-specific biomarkers.

详细描述

This is a Registry that invites patients undergoing colorectal surgery for colorectal cancer. Epidemiological data is collected. The Registry includes tumor tissue and blood samples banks used to studied different genetic variants and disease-specific biomarkers present in patients with Lynch syndrome and others hereditary cancers.

The aim of this registry is to set up the necessary resources to help basic and clinical research projects on colorectal cancer (CRC) within the Hospital Italiano de Buenos Aires (HIBA) and promote scientific collaborations between the HIBA and other institutions within and outside the country.

To make this project, the following specific goals are proposed:

Objective 1: Establishment of an efficient algorithm to enroll patients diagnosed with CRC from HIBA, through collaboration between the services of Surgery, Gastroenterology, Pathology, Oncology, Institute of Translational Medicine and Biomedical Engineering (IMTIB), Medical Clinic and Medical Informatics.

Objective 2: Development of logistics for the connection and expansion of the bank of biological samples (DNA, serum) and tumor samples (tissue fixed in formalin, frozen tissue) to the CRC.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
21 Years 至 96 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adult patients undergoing colorectal surgery for colorectal cancer.

排除标准

  • Unwillingness to participate.

结局指标

主要结局

Disease-free survival

时间窗: 5 years

The time free of disease recurrence will be estimated in the whole cohort and according to colorectal cancer stages and molecular profiles.

Overall survival

时间窗: 5 years

Patient overall survival at 5 years.

次要结局

  • Molecular characteristics of colorectal adenocarcinoma.(0)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Carlos Vaccaro

MD

Hospital Italiano de Buenos Aires

研究点 (2)

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