A Cohort of Molecular Characteristics and Prognosis of Colorectal Cancer
试验速览
- 阶段
- 不适用
- 入组人数
- 15,000
- 试验地点
- 1
- 主要终点
- Disease-free survival time
研究概览
简要总结
This study aims to establish a colorectal cancer cohort, collect clinicopathological information, collect biological samples for multi-omics testing, and perform relevant analysis, to predict the prognosis of colorectal cancer, guide the diagnosis and treatment of colorectal cancer and the formulation of health policies.
详细描述
In this study, the investigators will establish a database to collect clinical pathological information, based on the medical data system of participating medical centers. The investigators will also collect corresponding tumor specimens and perform multiple omics tests such as genome, transcriptome, and proteome. The investigators will aggregate these data into a special database, and use appropriate methods to conduct big data analysis, to predict prognosis, guide diagnosis and treatment, and assist in formulating health policies.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Pathologically diagnosed as colorectal cancer
- •Receiving any surgery of primary tumor, including palliative resection, simple enterostomy and exploratory surgery
排除标准
- •The patient refused to join the study
- •The patient refused to collect the biological sample
- •The patient refused to follow up
结局指标
主要结局
Disease-free survival time
时间窗: 2 yeas after surgery
For patients received radical resection of colorectal cancer, disease-free survival time is defined as time from the surgery to any recurrence of disease or death, recorded in months.
次要结局
- Overall survival time(2 yeas after surgery)
- Pathological TNM stage(1 month after surgery)