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临床试验/NCT02153463
NCT02153463已完成不适用

Enhancing Physical Activity in Children With Tics and Tourette Syndrome: Impact on Tic Severity and Quality of Life

Children's Hospital of Eastern Ontario2 个研究点 分布在 1 个国家目标入组 14 人开始时间: 2014年5月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
14
试验地点
2
主要终点
Decrease in Yale Global Tic Severity Scale.

研究概览

简要总结

Tics are brief repetitive movements or vocalizations. Gilles de la Tourette's syndrome (TS) is a disorder characterized by recurrent motor and vocal tics. Tourette syndrome and tic disorders affect up to 8% of children. Peak severity of tic disorders occurs between the ages of 8 to 12 years, therefore during childhood and adolescence the most significant impacts are felt. The quality of life of young people with tics is lower than their peers' and tic severity predicts lower quality of life. Studies have also shown negative social perception toward children with tics.

Approximately 50% of patients with Tourette syndrome will have other diagnoses including attention deficit hyperactivity disorder (ADHD), obsessive compulsive disorder, anxiety and depression. Studies have shown improvements in ADHD with physical activity. ADHD and tic disorders are thought to involve the same areas of the brain; thus it is possible that tics might also improve with physical activity. However, no studies to date have examined this. The investigators predict that by implementing a motivational physical activity program, in conjunction with physical activity counseling, the investigators will be able to increase levels of physical activity in children with tics and Tourette syndrome, with a positive impact on tic severity.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
8 Years 至 16 Years(Child)
性别
All
接受健康志愿者

入选标准

  • Participants are between 8-16 years of age.
  • Participants are required to have a diagnosis of either Tourette Syndrome or Persistent (Chronic) Motor of Vocal Tic Disorder as per the DSM V.
  • Participants must be ambulatory.
  • Participants and parents must understand English or French.
  • Participants must be able and willing to complete the questionnaires.
  • Participants cannot have any changes to their medication for tics, or any other psychotropic medications for 4 weeks prior to and for the entire duration of the study

排除标准

  • Participants who cannot ambulate independently.
  • Participants who are not permitted to participate in physical education class at school.
  • Participants or families who are not willing to be randomly assigned to a study group.

结局指标

主要结局

Decrease in Yale Global Tic Severity Scale.

时间窗: 8 weeks

次要结局

  • Change in The Gilles de la Tourette Syndrome Quality of Life Scale for children and adolescents(8 weeks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Asif Doja

Assistant Professor, Associate Investigator

Children's Hospital of Eastern Ontario

研究点 (2)

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