EUCTR2007-004856-35-GB进行中（未招募）1 期
Scavenging free haemoglobin atenuates the systemic inflmmatory response following surgery
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 入组人数
- 540
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •All patients over 16 years of age undergoing CPB for elective cardiac surgery at the Royal Brompton Hospital, London
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •Lack of informed consent
- •Cyanotic congenital heart disease (high haematocrit increases haemolysis)
- •Patients undergoing other extracorporeal interventions (ECMO, VAD, pre-admission dialysis)
- •Patients with congenital haemoglobinopathies (e.g. thalassaemia, cryoglobinuria)
- •Ppatients with disorders of iron metabolism (e.g. haemochromatosis)
- •Religious objections to transfusion of a plasma derived product
- •Patients with known blood borne infection.
- •Patients with known hypersensitivity to human albumin solution or gelofusine
研究者
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