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Optimizing anti coagulant therapy in neurosurgical interventions in patients with an increased risk for thrombo-embolic complications.

Recruiting
Conditions
abnormal blood clotting
vasculair illness
10009720
10014523
Registration Number
NL-OMON55381
Lead Sponsor
eids Universitair Medisch Centrum
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
280
Inclusion Criteria

Intracranial, tumour or trauma surgery,
>180 min estimates surgical intervention time
>240 min time under anaesthesia

Exclusion Criteria

Age under 18 years
Perioperative continuation of anti coagulant therapy indicated other than
prophylactic low molecular weight heparin

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>The primary goal of the current study is to investigate whether the combination<br /><br>of perioperative intermittent pneumatic compression and LMWH has a lower<br /><br>incidence of postoperative thrombo-embolic complications within a week after a<br /><br>high risk neurosurgical intervention in comparison to patients receiving merely<br /><br>LMWH prophylaxis.</p><br>
Secondary Outcome Measures
NameTimeMethod
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