Comparison of hospitalization time of patients with different treatments of deoulin nebulizer, deoulin nebulizer with inhalation spray and deoulin nebulizer and pulmicort simultaneously in patients with chronic obstructive pulmonary disease

Phase 2

Recruiting

Conditions: Chronic obstructive pulmonary disease.
Chronic obstructive pulmonary disease with (acute) exacerbation
J44.1

Registration Number: IRCT20210830052333N1

Lead Sponsor: Shahroud University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 174

Inclusion Criteria

Patients aged 18 to 80 years;
Patients with confirmed diagnosis of chronic obstructive pulmonary disease by spirometric and clinical findings;
Chronic illness for at least the last six months;
Do not take any antibiotics for at least the last month;
Conscious consent to participate in research.

Exclusion Criteria

Loss of consciousness;
Severe restlessness;
Severe respiratory distress with oxygen pressure less than 60 mm Hg and carbon dioxide pressure greater than 45 mm Hg in a venous gas sample;
Severe heart failure;
Pulmonary embolism;
Use of any opium in the past month;
Existence of severe infectious diseases of the respiratory tract for at least one month;
History of any surgery on the respiratory tract.

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The amount of hospitalization hours in the emergency department. Timepoint: Once an hour. Method of measurement: Count the hours of hospitalization.;Measuring the extent of disease severity reduction. Timepoint: Once an hour. Method of measurement: By counting the number of breaths per minute.;Maximum expiratory volume per the first second (FEV1). Timepoint: Once an hour. Method of measurement: Micromedical spirometer.

Secondary Outcome Measures

Name	Time	Method
Measurement of arterial blood oxygen saturation. Timepoint: Once an hour. Method of measurement: Arterial blood oxygen measurement test with ABG device.;Measurement of venous blood carbon dioxide saturation. Timepoint: Once an hour. Method of measurement: Carbon dioxide test with ABG device.