Acute Stroke Program of Interventions Addressing Racial and Ethnic Disparities

Completed

• Conditions: Stroke

• Registration Number: NCT00724555
• Lead Sponsor: Georgetown University

Brief Summary

The purpose of this study is to increase treatment of acute stroke with tissue plasminogen activator (tPA) across the District of Columbia. This study, however, will not evaluate tPA as an intervention.

Detailed Description

There are a number of well-known barriers to receiving tissue plasminogen activator (tPA) including transit time to hospital, paramedic and provider training, tPA standing orders, and provider guidelines. Among underserved populations, limited stroke knowledge, socioculturally determined attitudes, and beliefs and myths held by community members may serve as additional barriers that hinder these populations from receiving tPA and acute stroke care. Targeted multilevel interventions designed to overcome specific barriers may significantly increase the number of individuals with stroke who are appropriately treated with intravenous tPA (IV tPA) in underserved communities. Identification of the specific components of healthcare interventions that are the most effective is critical to improve delivery of acute stroke therapy.

The goal of this study is to learn more about public knowledge, attitudes, beliefs and perceptions regarding stroke and stroke treatment in order to identify sociocultural and environmental barriers to receiving tPA and acute stroke care in an underserved community. This study will also determine if implementation of a multilevel intervention program can significantly increase the number of people with ischemic stroke who are appropriately treated with IV tPA in a predominantly underserved community.

In the study, researchers will evaluate the different levels of the intervention to determine which efforts are most effective.

Study Timeline

• Study Start: 2008-02
• Study First Submitted: 2008-07-28
• Study First Submitted QC: 2008-07-28
• Study First Posted: 2008-07-29
• Primary Completion: 2013-01
• Study Completion: 2013-01
• Status Verified: 2014-01
• Last Update Submitted: 2014-01-30
• Last Update Posted: 2014-01-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 2005

Inclusion Criteria

• diagnosis of acute ischemic stroke
• over the age of 18

Exclusion Criteria

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The proportion of people with ischemic stroke appropriately treated with IV tPA.	4 years

Secondary Outcome Measures

Name	Time	Method
Qualitative data collected from the community will identify baseline levels of knowledge, attitudes, and perceived and encountered barriers to acute stroke treatment.	1 year

Trial Locations

Locations (8)

Sibley Memorial Hospital; 🇺🇸 Washington, District of Columbia, United States

George Washington University Hospital; 🇺🇸 Washington, District of Columbia, United States

Georgetown University, ASPIRE Coordinating Center; 🇺🇸 Washington, District of Columbia, United States

Columbia University Medical Center; 🇺🇸 New York, New York, United States

United Medical Center (formerly known as Greater Southeast Community Hospital); 🇺🇸 Washington, District of Columbia, United States

Washington Hospital Center; 🇺🇸 Washington, District of Columbia, United States

Providence Hospital; 🇺🇸 Washington, District of Columbia, United States

Howard University Hospital; 🇺🇸 Washington, District of Columbia, United States