Project to Improve the Diagnosis and Treatment Ability of Adult Severe Community Acquired Lower Respiratory Tract Infection

Completed

• Conditions: CAP; COPD Exacerbation

• Registration Number: NCT04959955
• Lead Sponsor: Peking University Third Hospital

Brief Summary

1. Objective to understand the proportion of atypical pathogens in the pathogens of SCAP and AECOPD in urban hospitals in China.

2. Objective to investigate the antimicrobial resistance of atypical pathogens in patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) and SCAP in urban hospitals.

3. Objective to master the important clinical characteristics of patients with acute exacerbation of SCAP and COPD caused by atypical pathogens and mixed infection in urban hospitals in China, and to put forward the experience judgment index.

4. Objective to evaluate the advantages of various diagnostic methods for atypical pathogens causing lower respiratory tract infection.

5. It is suggested that the current empirical treatment of SCAP and severe COPD in China should be improved.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-08-08
• Primary Completion: 2016-07-10
• Study Completion: 2019-12-12
• Status Verified: 2021-07
• Study First Submitted: 2021-07-04
• Study First Submitted QC: 2021-07-04
• Last Update Submitted: 2021-07-04
• Study First Posted: 2021-07-13
• Last Update Posted: 2021-07-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• SCAP
• AECOPD

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Exclusion Criteria

• Pregnant or lactating women.

  • Patients with bronchiectasis.

    • Patients with active pulmonary tuberculosis.

      • Aspiration pneumonia or obstructive pneumonia.

        • Two weeks before the onset of hospital treatment history, this infection can not be excluded from hospital acquired infection.

          • HIV positive patients (but HIV testing is not required).

            • Patients who are unable and / or unable to understand and / or implement the investigation protocol.

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of atypical pathogens and mixed infections	2year Incidence	Incidence of atypical pathogens and mixed infections