Silodosin in Management of Lower Ureteral Stones

Phase 1

Completed

• Conditions: Stone, Kidney
• Interventions: Drug: Silodosin

• Registration Number: NCT06381206
• Lead Sponsor: Syrian Private University

Brief Summary

This research aims to study the effectiveness of silodosin in the management of lower ureter stones larger than 6 mm in diameter in terms of affected ureter (right or left), the size of the stone, the degree of hydronephrosis, the rate of stone expulsion(day), whether the stone was completely expelled or not, and the side effects of silodosin.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-10-20
• Primary Completion: 2023-10-20
• Study Completion: 2023-10-25
• Study First Submitted: 2024-02-09
• Status Verified: 2024-04
• Study First Submitted QC: 2024-04-19
• Last Update Submitted: 2024-04-19
• Study First Posted: 2024-04-24
• Last Update Posted: 2024-04-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Patients attending the urology Clinic with a distal unilateral ureteral stone larger than 6 mm in diameter.

Exclusion Criteria

• Patients under 18 years of age
• Pregnant women
• Patients with whom we were unable to contact
• Patients treated with silodosin for another reason
• Single kidney patients
• Patients with bilateral ureter stones
• Patients with deteriorating kidney function
• Patients with grades 3rd and 4th of hydronephrosis

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
case group	Silodosin	patients who had given silodosin

Primary Outcome Measures

Name	Time	Method
Stone expulsion (yes)	1 year	patients who were able to expel the stone
Stone expulsion (no)	1 year	patients who were not able to expel the stone

Trial Locations

Locations (1)

Damascus university; 🇸🇾 Damascus, Syrian Arab Republic