A clinical trial to study the effects of two drugs, Diclofenac and Ketoprofen, which are used to reduce pain in postoperative upper limb orthopedic surgeries
Phase 3
- Conditions
- Health Condition 1: G891- Acute pain, not elsewhere classifiedHealth Condition 2: M968- Other intraoperative and postprocedural complications and disorders of musculoskeletal system, not elsewhere classified
- Registration Number
- CTRI/2022/12/047868
- Lead Sponsor
- nil
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Subjects willing to give written informed consent.
2. Adults above 18 years and below 65 years of age of either gender.
3. Subjects who are undergoing upper limb fracture fixation surgery.
Exclusion Criteria
1. Subjects having history of heart block, bronchial asthma, bleeding disorders, on anticoagulants, active peptic ulcer disease, skin diseases, liver and kidney disorders and drug/alcohol abuse
2. Pregnant and Lactating mothers
3. Subjects with hypersensitivity to the study medications
4. Subjects with poly trauma.
5. Subjects operated under general anaesthesia.
6. Subjects with contraindications to regional block.
7. Subjects with history of peripheral neuropathy and pre-existing nerve damage in the operative arm
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Postoperative pain assessment using Verbal Rating Scale and Numerical Rating ScaleTimepoint: 0hour, 4hour, 8hour, 12hour and 24hour postoperative period
- Secondary Outcome Measures
Name Time Method eed for rescue analgesicTimepoint: Within the first 24hour postoperative period;Timing of rescue analgesic administrationTimepoint: From the time of surgery