Subjective/Psychomotor/ Effects of Combined Alcohol & Nitrous Oxide - 16

Not Applicable

Completed

• Conditions: Opioid-Related Disorders; Substance-Related Disorders
• Interventions: Drug: 30% Nitrous oxide; Other: 0.35 g/Kg ethanol; Other: 0 g/Kg ethanol; Other: 0.7 g/Kg ethanol

• Registration Number: NCT00000264
• Lead Sponsor: University of Chicago

Brief Summary

The purpose of this study is to examine the subjective, psychomotor, and reinforcing effects of combined alcohol and nitrous oxide intake in healthy volunteers.

Detailed Description

Not available

Study Timeline

• Study Start: 1997-09
• Study First Submitted: 1999-09-20
• Study First Submitted QC: 1999-09-20
• Study First Posted: 1999-09-21
• Primary Completion: 1999-10
• Study Completion: 1999-10
• Status Verified: 2015-05
• Last Update Submitted: 2015-05-26
• Last Update Posted: 2015-05-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 8

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
0.35 g/Kg ethanol +/- 30% nitrous oxide	0.35 g/Kg ethanol	-
0.35 g/Kg ethanol +/- 30% nitrous oxide	30% Nitrous oxide	-
0 g/Kg ethanol +/- 30% nitrous oxide	30% Nitrous oxide	-
0 g/Kg ethanol +/- 30% nitrous oxide	0 g/Kg ethanol	-
0.7 g/Kg ethanol +/- 30% nitrous oxide	0.7 g/Kg ethanol	-
0.7 g/Kg ethanol +/- 30% nitrous oxide	30% Nitrous oxide	-

Primary Outcome Measures

Name	Time	Method
Mood	Baseline and post inhalation
Psychomotor performance	Baseline and post inhalation
Cognitive performance	Baseline and post inhalation
Choice of nitrous oxide vs placebo	after each ethanol session

Trial Locations

Locations (1)

University of Chicago, Anesthesia & Critical Care; 🇺🇸 Chicago, Illinois, United States