The Effect of Pre-incisional Anterior Scalp Block on Intraoperative Opioid Consumption in Adult Patients Undergoing Elective Craniotomy to Remove Tumor: A Prospective Randomized Controlled
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Intraoperative opioid consumption
研究概览
简要总结
Anterior scalp block with 0.5% plain Marcaine 20 ml. may reduce the intraoperative opioid consumption in neurosurgical patients who undergoing the supratentorial craniotomy compared to those who receive 0.9% normal saline solution (placebo).
详细描述
Anterior scalp block with 0.5% plain Marcaine 20 ml. may reduce the intraoperative opioid consumption in neurosurgical patients who undergoing the supratentorial craniotomy compared to those who receive 0.9% normal saline solution (placebo).
A Prospective Randomized Double Blind Control
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients who have supratentorial brain tumor
- •Patients have been scheduled to undergo an elective craniotomy to remove tumor in any surgical position
- •Patients have been general anesthetized with endotracheal intubation and control ventilation
- •Patients who have provided consent for the participation in the research and for the use of their medical record in research
排除标准
- •Pregnant patients
- •Patients who have a history of local anesthetic allergy and/ or anaphylaxis
研究组 & 干预措施
Scalp block with 0.5% plain marcaine
Anterior scalp block with 0.5% plain Marcaine 20 ml.
干预措施: Scalp block with 0.5% plain Marcaine (Drug)
Scalp block with 0.9% normal saline
Anterior scalp block with 0.9% normal saline 20 ml.
干预措施: Scalp block with 0.9% normal saline (Drug)
结局指标
主要结局
Intraoperative opioid consumption
时间窗: During the supratentorial craniotomy surgery
The overall intravenous fentanyl consumption (microgram/ kilogram) during the surgery. The decision to administer fentanyl is guided by the changes of blood pressure and/ or heart rate greater than 20% from baseline level.
次要结局
- Heart rate change(within 5 minutes after skull pin insertion)
- systolic blood pressure change(within 5 minutes after skull pin insertion)
研究者
Pathomporn Pin on, M.D.
Department of Anesthesiology
Chiang Mai University