Diagnosis and Prognosis of Traumatic Brain Injury Outcome using Magnetic Resonance Imaging

niversity of Queensland0 sites300 target enrollmentDecember 17, 2020

Overview

No summary available.

Registry

who.int

Start Date

December 17, 2020

End Date

TBD

Last Updated

2 years ago

Study Type

Observational

Sex

All

Sponsor

niversity of Queensland

•1\.Age greater than or equal to 18 years old
•2\.Diagnosed with moderate or severe TBI\*, with or without other injuries.
•\*TBI Definition \- A TBI will be defined based on the post\-resuscitation Glasgow Coma Scale (GCS) in the pre\-hospital period and the first 24 hours of ICU admission, if admitted to ICU. Moderate and Severe TBI are defined by the following categories of GCS if in the opinion of the treating team GCS is not solely due to intoxication, sedation, or extracranial injury
•Moderate TBI is defined as a GCS score of 9\-12
•Severe TBI is defined as a GCS score of less than or equal to 8

•1\. Previous major stroke
•2\. Pregnancy, or may be pregnant
•3\. In the opinion of the investigator the participant would be unlikely to be able to comply with study procedures and follow up (e.g. lives overseas).
•4\. Presence of underlying disease with a life expectancy of less than 6 months
•5\. Known contraindication to MRI that will prevent study procedures
•6\. Patients who have suffered a devastating TBI with either progression towards brain death at the time of assessment or where the treating medical team are not committed to ongoing full supportive care
•7\. Traumatic brain injury occurred more than 72 hours ago