High Dose and Low Dose of Atorvastatin in Patients With Unstable Angina and NSTEMI (Non ST Elevation MI)
Not Applicable
Completed
- Conditions
- Cardiovascular Disease
- Interventions
- Registration Number
- NCT01306565
- Lead Sponsor
- Hormozgan University of Medical Sciences
- Brief Summary
The aim of this study is to compare the effect of high dose and low dose of Atorvastatin in reduction level of C-reactive protein (CRP) in patients with unstable angina and NSTEMI (Non ST Elevation MI) attending Shahid Mohammadi hospital in Bandar Abbas.
- Detailed Description
This study compare the effect of 80mg atorvastatin followed by two 20mg daily atorvastatin with three 80mg daily atorvastatin in reduction of CRP in patients with unstable angina and NSTEMI (Non ST Elevation MI) attending Shahid Mohammadi hospital in Bandar Abbas in 2009.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
- Patients with unstable angina with chest discomfort at rest with normal EKG or St depression (at least 0.1mv) in two consecutive leads or new and deep T inversion (at least 0.2mv)
Exclusion Criteria
- Myocardial Infarction with ST elevation
- Diabetes Mellitus
- Previous statin use
- Current infectious disease
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description High dose atorvastatin Low dose Atorvastatin Three 80mg daily doses of atorvastatin Low dose Atorvastatin High dose atorvastatin 80mg atorvastatin followed by two 20mg daily atorvastatin
- Primary Outcome Measures
Name Time Method CRP reduction 72 hours CRP reduction will be compared between two study groups
- Secondary Outcome Measures
Name Time Method Drug side effects 72 hours Headache, Myopathy
Trial Locations
- Locations (1)
Hormozgan University of Medical Sciences
🇮🇷Bandar Abbas, Hormozgan, Iran, Islamic Republic of