Improving the Clinical Management of Stable Chest Pain Based on Imaging: a Registry of Computed Tomography Coronary Angiography
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 50,000
- 试验地点
- 4
- 主要终点
- Major adverse cardiovascular events
研究概览
简要总结
The investigator aims to prospectively enroll patients who were referred for coronary computed tomography angiography (CCTA) for the assessment of stable chest pain (SCP) suspected of obstructive coronary artery disease (CAD). All patients underwent CCTA according to established guidelines and local institutional protocols. The imaging data were evaluated using different image post-processing software to comprehensively analyse anatomical, functional and histological information of coronary. This study will determine if CCTA-based imaging evaluation can provide more informaton to improve clinical management for SCP, including fewer MACE and better decision-making of downstream investigations and therapeutic interventions.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •symptomatic patients with SCP suspected of obstructive CAD.
- •referred for CCTA for the assessment of SCP.
- •≥18 years of age.
- •signed informed consent.
排除标准
- •acute coronary syndromes
- •previous CAD or coronary revascularization
- •nonsinus rhythm
- •cardiomyopathy, valvular disease, congenital heart disease or left cardiac insufficiency because of other reasons
结局指标
主要结局
Major adverse cardiovascular events
时间窗: 10 years
Cardiac death and myocardial infarction
次要结局
- Medication prescription(10 years)
- Coronary revascularization(10 years)
- Number of Participants with Death(10 years)
- Invasive coronary angiography(10 years)
- Number of Participants with Stroke(3 years)
- Number of Participants with Cardiac death(10 years)
- Number of Participants with Myocardial infarction(10 years)
研究者
Zhou Jia
Doctor
Tianjin Chest Hospital