Resonance Breathing and Postural Resonance: Acute Modulation of Autonomic and Hemodynamic Responses Via Arterial Baroreflex Mechanisms
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Skin sympathetic nerve activity
研究概览
简要总结
This study aimed to compare the acute autonomic and hemodynamic effects of two arterial baroreflex resonance interventions-Resonance Breathing (RB) and Postural Resonance (PR)-in healthy young adults. Methods: A randomized crossover design was conducted in 27 healthy participants (aged 18-25). Each participant completed three experimental sessions (control, RB, and PR) separated by a 5-day washout period. Each session included a 15-minute baseline, a 15-minute intervention, and a 5-min recovery phase. Continuous recordings of skin sympathetic nerve activity (SKNA) and heart rate variability (HRV) were collected throughout each session, while blood pressure (BP) and pulse wave velocity (PWV) were measured before and after the interventions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18-30 years old
排除标准
- •No history of systematic professional sports training; Right-hand dominance (as assessed by the Edinburgh Handedness Inventory). Participants were excluded from the study if they had any of the following: Smoking, chronic alcohol consumption, or the use of psychotropic drugs or other substances affecting the nervous system; Irregular menstrual cycle; History of peripheral neuropathy or other autonomic nervous system disorders; Pre-existing cardiovascular diseases or abnormal electrocardiograms (ECG); Use of hormonal contraceptives; Uncontrolled hypertension or hypotension; Recent major life stressors; Regular practice of meditation or participation in psychotherapy; Presence of any movement disorders or inability to comprehend the experimental instructions.
研究组 & 干预措施
Intervention Arm
Participants receive structured Resonance Breathing and Postural Resonance training aimed at modulating baroreflex function, autonomic balance, and hemodynamic responses. All measurements are conducted at baseline and following intervention.
干预措施: Resonance Breathing (Behavioral)
Intervention Arm
Participants receive structured Resonance Breathing and Postural Resonance training aimed at modulating baroreflex function, autonomic balance, and hemodynamic responses. All measurements are conducted at baseline and following intervention.
干预措施: Postural Resonance (Behavioral)
结局指标
主要结局
Skin sympathetic nerve activity
时间窗: Baseline (pre-intervention) and immediately post-intervention (within 5 minutes of intervention completion)
Skin sympathetic nerve activity (SKNA) was recorded non-invasively at the chest wall using a dedicated SKNA monitoring system. Measurements were obtained at baseline (pre-intervention) and immediately following completion of the resonance breathing and postural resonance intervention, to assess acute changes in sympathetic nervous system activity.
次要结局
- Changes in Resting Systolic and Diastolic Blood Pressure(Baseline (pre-intervention) and immediately post-intervention (within 5 minutes of intervention completion))
- Changes in Pulse Wave Velocity (PWV)(Baseline (pre-intervention) and immediately post-intervention (within 5 minutes of intervention completion))