Evolution of Pulsed Oxygen Saturation During Interval Training Compared to Continuous Training in COPD Patients

Recruiting

• Conditions: COPD; Exercise; Desaturation of Blood; Pulmonary Rehabilitation

• Registration Number: NCT05825638
• Lead Sponsor: Groupe Hospitalier du Havre

Brief Summary

A problem often observed during exercise training is oxygen desaturation exclusively during exercise in some patients. In the case of exercise-induced desaturation, it may be suggested to train these patients in interval training to limit exercise-induced desaturation. Interval training consists of alternating active phases of short duration (often 30 seconds to 1 minute) followed by a short active or passive recovery phase of equivalent duration to the previous phase. Investigators therefore hypothesise that interval training on a cycloergometer or treadmill can limit exercise-induced desaturation in COPD patients.

The aim of the study is to observe the evolution of pulsed oxygen saturation between a continuous training session and a interval training session.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-01-10
• Study First Submitted: 2023-01-10
• Status Verified: 2023-04
• Study First Submitted QC: 2023-04-11
• Last Update Submitted: 2023-04-11
• Study First Posted: 2023-04-24
• Last Update Posted: 2023-04-24
• Primary Completion: 2024-01
• Study Completion: 2024-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

• a diagnosis of COPD
• participating in a pulmonary rehabilitation programme
• with an exercise-induced desaturation less than 90%
• no oxygen supplementation

Exclusion Criteria

• Under 18 years of age
• Pregnant woman
• Person not affiliated to a health insurance regime or not benefiting from a social security regime
• Patient under curatorship, guardianship or safeguard of justice
• Patient speaking a language other than French
• Patient with severe hypoxaemia (SpO2 ≤ 80%) during exercise
• Patient having had a moderate or severe exacerbation (hospitalisation for respiratory reasons) in the previous 4 weeks
• Patients with orthopaedic, rheumatic, vascular or neurological pathology limiting their ability to make an effort
• Breastfeeding women

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Difference in oxygen pulsed saturation	One week	Difference in minimum saturation during both exercise, the measurement will be performed with a pulse oximeter (Spirodoc, MIR)

Secondary Outcome Measures

Name	Time	Method
Difference in oxygen pulsed saturation	One week	Difference in mean pulsed oxygen saturation and the time spent with a pulsed oxygen saturation below 90% during the two training sessions. The measurement will be performed with a pulse oximeter (Spirodoc, MIR)
Difference in respiratory rate	One week	Difference in respiratory rate will be measured breath-by-breath using a portable spirometer (Spirodoc, MIR)
Difference in tidal volume	One week	Difference in tidal volume will be measured breath-by-breath using a portable spirometer (Spirodoc, MIR)
Difference in peripheral muscle oxygenation	One week	Muscle oxygenation (arbitrary unit) will be evaluated using Near-infrared spectroscopy technology. the measurement will be performed with a Near Infrared spectroscopy (Portamon, Artinis Medical Systems)
Difference in inspiratory capacity	One week	Difference in inspiratory capacity will be measured using a portable spirometer (Spirodoc, MIR)
Difference in muscle discomfort	One week	Muscle discomfort peak during exercise using the modified Borg scale 0-10, 0 no dyspnea, 10 maximal dyspnea
Difference in Dyspnea	One week	Dyspnea peak during exercise using the modified Borg scale 0-10, 0 no dyspnea, 10 maximal dyspnea

Trial Locations

Locations (1)

Groupe Hospitalier du Havre; 🇫🇷 Le Havre, Normandie, France