Effects of Exercise-intensity on Physiological Adaptations in Overweight and Obese

Norwegian University of Science and Technology1 site in 1 country30 target enrollmentOctober 2011

ConditionsOverweight Obesity

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Overweight
Sponsor: Norwegian University of Science and Technology
Enrollment: 30
Locations: 1
Primary Endpoint: Maximal oxygen uptake
Status: Completed
Last Updated: 9 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The main purpose of our study is to examine the physiological adaptations in oxygen transport chain for high-intensity exercise and moderate exercise in overweight and obese humans. The main goals are:

To investigate the most effective short-and long-interval training in terms of VO2max, pulmonary diffusion, cardiac output, endothelial function and mitochondrial function.
How these physiological adaptations affect the aerobic endurance and performance, and how this training can reduce the risk of cardiovascular diseases related to overweight and obesity.

Registry

clinicaltrials.gov

Start Date

October 2011

End Date

December 2012

Last Updated

9 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Norwegian University of Science and Technology

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•BMI \> 25

Exclusion Criteria

•Exclusion criteria will be cardiovascular disease or another disease that is not consistent with high physical activity. Subjects should not have exercised regularly before the study.

Outcomes

Primary Outcomes

Maximal oxygen uptake

Time Frame: 6 weeks

Change in maximal oxygen uptake will be measured after six weeks of various exercise training and related to changes in blood volume, cardiac function, endothelial function and mitochondrial function.