Direct Identification of Anastomotic leakage with Microdialysis in Abdominal surgery

Completed

• Conditions: maagdarmstelsel diagnostiek; Anastomotic leakage; peritonitis

• Registration Number: NL-OMON31648
• Lead Sponsor: Reinier de Graaf Groep

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 202

Inclusion Criteria

Planned esophagectomy and gastric pull-up for preoperative T1-3N0-1M0 esophagus carcinoma, pancreaicoduodenectomy for resectable pancreatic or biliairy neoplasm, sigmoid or rectumresection for adenoma or carcinoma. Patients are capable of making decisions autonomously.
ASA class 1,2 and 3.

Exclusion Criteria

ASA 4-5
<18 yr/old

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Determination of near anastomotic postoperative levels of pyruvate, lactate,<br /><br>glycerol and glucose by micodialysis after esophagectomy and gastric pull-up.<br /><br>Determination of postoperative levels of pyruvate, lactate, glycerol and<br /><br>glucose by micodialysis of peritoneal fluid after sigmoid or rectum resection.<br /><br>Determination of near anastomotic postoperative pyruvate, lactate, glycerol and<br /><br>glucoselevels by micodialysis after pancreaticoduodenectomy.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Determination of postoperative levels of pyruvate, lactate, glycerol and<br /><br>glucose in case of anastomotic leakage after sigmoid or rectum resection.<br /><br>Correlation of microdialysis values to clinical and diagnostic findings.</p><br>