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Early Detection of Anastomotic Leakage after Colon, Esophageal and Gastric Surgery

Withdrawn
Conditions
Anastomotic dehiscence
Anastomotic leakage
10017998
10069888
Registration Number
NL-OMON37065
Lead Sponsor
Atrium Medisch Centrum
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Withdrawn
Sex
Not specified
Target Recruitment
308
Inclusion Criteria

Patients who will undergo one of the following types of surgery will be included:
- (partial) colectomy with a primary anastomosis
- esophagectomy with gastric interposition
- (partial) gastrectomy

Exclusion Criteria

Previous gastro-intestinal surgery in the last 2 months.

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>The following serum blood values will be measured and their relationship with<br /><br>anastomotic leakage will be analyzed between patients with anastomotic leakage<br /><br>and control patients without anastomotic leakage.<br /><br><br /><br>* Leucocyte count and differentiation<br /><br>* C-reactive protein<br /><br>* Procalcitonin<br /><br>* Lactate<br /><br>* Creatinin<br /><br><br /><br>The outcome of the study is the occurrence of anastomotic leakage confirmed by<br /><br>CT, water soluble enema, explorative surgery or pathology within 28 days after<br /><br>initial surgery. </p><br>
Secondary Outcome Measures
NameTimeMethod
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