Early Versus Routine Abdominal Drain Removal After Live Liver DonorHepatectomy

Phase 2/3

Recruiting

• Conditions: Live Liver Donors undergoing surgery; Medical and Surgical,

• Registration Number: CTRI/2021/01/030702
• Lead Sponsor: ILBS

Brief Summary

Prophylacticabdominal drainage after donor right hepatectomy for LDLT has been a common oreven mandatory practice in most transplant centres. This serves to monitor theoccurrence of postoperative intra abdominal bleeding and is used for thedetection and drainage of any bile leakage. However drain placement is notwithout any disadvantages like infective complications, increased pain, andprolonged hospital stay and bowel injury. In a study on non transplant liverresections by mitsuka et al, they validated 3x3 rule and concluded that therule is clinically feasible andallows for the early removal of the drain tube with minimum infection riskafter liver resection. There is no study done on live donor liver resection, interms of drain removal. We are doing a randomized control trial tocompare the safety of early drain removal versus standard drain removal afterdonor hepatectomy in terms of donor outcomes. We will analyse the data and elucidatethe safety of early drain removal using 3x3 rule with routine drain removal.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-01-28
• Last Update Posted: 2022-01-20

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

live donor undergoing donor hepatectomy.

Exclusion Criteria

left lateral hepatectomy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
safety of early drain removal	3 months
complications compared between both group using CCI.	3 months

Secondary Outcome Measures

Name	Time	Method
bile leak	3 months
readmission and reintervention rate	30 days
bowel injury	3 months
post operative pain score	30 days
post op hospital stay	15 days

Trial Locations

Locations (1)

institute of liver and biliary sciences; 🇮🇳 Delhi, DELHI, India

institute of liver and biliary sciences

🇮🇳Delhi, DELHI, India

Parthiban

Principal investigator

7010752115

parthid2005@gmail.com