Effect of Ibuprofen, dexamethasone and placebo on lower jaw nerve anesthesia
Phase 3
- Conditions
- Irreversiblae pulpitis.Diseases of pulp and periapical tissues
- Registration Number
- IRCT201011085141N1
- Lead Sponsor
- Periodontal and dental research center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Other
- Sex
- All
- Target Recruitment
- 210
Inclusion Criteria
healthy patients having a first or second mandibular molar tooth with irreversible pulpitis and normal periapical radiographic appearance. Exclusion criteria: the presence of systemic disorders, a sensitivity to lidocaine with 1:80,000 epinephrine; a sensitivity to NSAIDs; nasal polyp; a history of gastrointestinal ulcers; the presence of widening of the periodontal ligament space; the presence of a periapical radiolucency; lactation, pregnancy; using any type of analgesic medication in the preceding 12 hours before the treatment; having a tooth not suitable for restoration, and having a full crown.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Inferior alveolar nerve block. Timepoint: 45 minute after intervention (15 minute after injection). Method of measurement: visual analoge scale.
- Secondary Outcome Measures
Name Time Method Analgesia during access cavity preparation and entrance into the root canal. Timepoint: during access cavity preparation and entrance into the root canal. Method of measurement: visual analoge scale.