The evaluation of cheese vs milk for stimulating post-prandial and post-exercise muscle protein synthesis

Completed

• Conditions: Muscle mass growth; which can be related to sarcopenia

• Registration Number: NL-OMON28444
• Lead Sponsor: Maastricht University

Brief Summary

https://doi.org/10.1093/jn/nxac007

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

•Healthy males
•Age between 18 and 35 y inclusive
•BMI between 18.5 and 30 kg/m2

Exclusion Criteria

•Allergies to milk proteins
•Lactose intolerant
•Smoking
•Phenylketonuria
•Diabetes Mellitus
•Diagnosed GI tract disorders or diseases
•Arthritic conditions
•A history of neuromuscular problems
•Any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications).
•Use of certain anticoagulants (use of thrombocyte aggregation inhibitors such as acetylsalicylic acid and carbasalaatcalcium is permitted. Use of other thrombocyte aggregation inhibitors will be discussed with the responsible physician)
•Blood donation within 2 months of study initiation
•Hypertension (according to WHO criteria)
•Recent participation in amino acid tracer studies (less than 1 year ago)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
MPS and plasma AA availability

Secondary Outcome Measures

Name	Time	Method
whole-body protein synthesis, breakdown, oxidation, and net balance, plasma glucose and insulin, and metabolic signalling