Postprandial Effects of Milk and Milk Constituents

Not Applicable

Completed

• Conditions: Hyperlipidemia; Inflammation
• Interventions: Dietary Supplement: Control; Dietary Supplement: Calcium; Dietary Supplement: Milk; Dietary Supplement: Protein

• Registration Number: NCT00917878
• Lead Sponsor: Maastricht University Medical Center

Brief Summary

The purpose of this study is to determine whether the addition of milk or the milk constituents calcium and protein to a high-fat breakfast affects the postprandial lipid and inflammatory response.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-03
• Study First Submitted: 2009-06-08
• Study First Submitted QC: 2009-06-08
• Study First Posted: 2009-06-10
• Primary Completion: 2009-07
• Study Completion: 2009-07
• Status Verified: 2009-09
• Last Update Submitted: 2018-04-25
• Last Update Posted: 2018-04-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 16

Inclusion Criteria

• Body mass index (BMI) above 27 kg/m2

Exclusion Criteria

• Smoking
• Diabetes mellitus
• Cardiovascular diseases
• Familial hypercholesterolemia or lipid lowering medication
• Severe conditions that might interfere with the study outcomes, such as COPD, asthma, rheumatoid arthritis, etc.
• Unstable body weight
• Abuse of alcohol or drugs
• Participation in another biomedical study during the past 30 days
• Having donated blood during the past 30 days

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Control	Control	Lactose in 500 mL water added to high-fat meal (control condition)
Calcium	Calcium	Milk calcium in 500 mL water added to high-fat meal
Milk	Milk	500 mL low-fat milk added to high-fat meal
Protein	Protein	Milk protein in 500 mL water added to high-fat meal

Primary Outcome Measures

Name	Time	Method
Plasma inflammatory markers	6 h after meal

Secondary Outcome Measures

Name	Time	Method
Serum lipids	6 h after meal

Trial Locations

Locations (1)

Maastricht University Medical Center; 🇳🇱 Maastricht, Netherlands